Prescribing ALLO Products

Note: The following information is directed to healthcare practitioners and not for consumers. Please discuss the use of NVP products with your general practitioner.

ALLO SYNC Pod System

  • Available in 3 flavours: Tobacco, Mint, and Unflavoured.
  • Available in 3 nicotine strengths: 0mg/ml, 20mg/ml, and 30mg/ml.

Dosage and Self-titration

  • As with any NVP product, user behaviour and experience level will determine the total nicotine delivered.
  • Due to the rapid delivery of nicotine, accurate and sufficient self-titration should be possible for most patients.
  • All evidence shows that user experience is the single most defining factor in an NVP user’s ability to gain a cigarette-like nicotine PK profile from the technology.

Instructions to Lower Learning Curve:

  1. Ensure you take a sufficient length of puff (1-3 seconds) and inhale deeply.
  2. If you find you are still craving after two puffs with a 20-second interval between them, on a third puff, try holding your breath for 4 or 5 seconds before exhaling.
  3. Try to take no more than ten puffs per hour.
  4. If you find you are taking more than this, try taking longer puffs (but no more than 3 seconds) and vary the inhalation depth and the length of time before exhaling.
  5. While starting on NVPs, it is essential to use them every day. If you can’t substitute completely immediately, aim to replace specific cigarettes, such as the day’s first cigarette, and increase the substitution over time.

Initial Prescription - ALLO SYNC

  • Clinicians should initially prescribe one ALLO Sync per day for all patients who qualify for treatment, regardless of the number of cigarettes the patients smoke.
  • Patients should be provided with a prescription for three months’ supply of ALLO Sync Pods as the consultation determines.
    • 10 x 3-packs at one pod per day initial prescription with 3 x repeats.
    • Maximum one pod per day.

Example Prescription

  • During the follow-up consultation (recommended for three months after the initial consultation), clinicians should ask patients about the number of cartridges they consume per day and adjust, as necessary, the number of ALLO Pods prescribed subsequently.

Tolerance and Nicotine Strength Considerations

  • ALLO NVP products have sensory characteristics that should be tolerable for most people who smoke.
  • For patients who cannot tolerate higher nicotine strengths, the lower 20mg/ml or 30mg/ml ALLO NVP may be appropriate.
  • Clinicians should bear in mind:
    • Research shows that lower concentrations of nicotine in cartridge systems do not deliver the same subjective positive effects. For new users, this may cause a failure to adhere to treatment.
    • Since smokers self-titrate, there may be insufficient nicotine in one cartridge for patients to maintain craving relief throughout the day, with the attendant risk of relapse.
    • Before prescribing lower nicotine strength (20mg/ml or 30mg/ml) ALLO SYNC to a recently initiated user, it is advisable to see if they have tried using an alternative flavour, as this may enable them to tolerate the higher nicotine strength.